Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder-Reference-Cited by-同舟云学术

Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder

Published:2020-07-14 Issue:12 Volume:60 Page:1642-1654
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Lalovic Bojan¹,Majid Oneeb²,Aluri Jagadeesh¹,Landry Ishani¹,Moline Margaret¹,Hussein Ziad²

Affiliation:

1. Eisai Inc. Woodcliff Lake New Jersey USA

2. Eisai Ltd. Hatfield UK

Funder

Eisai Inc

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcph.1683

Reference45 articles.

1. Epidemiology of insomnia: what we know and what we still need to learn

2. Insomnia in primary care patients;Shochat T;Sleep,1999

3. Insomnia and Its Treatment

4. Epidemiological and clinical relevance of insomnia diagnosis algorithms according to the DSM-IV and the International Classification of Sleep Disorders (ICSD)

5. Daytime sleepiness and insomnia as correlates of depression;Fava M;J Clin Psychiatry,2004

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Emerging and upcoming therapies in insomnia;Translational and Clinical Pharmacology;2024

2. Exposure–Response Analyses of Polysomnography and Subjective Sleep Efficacy End Points From the Phase 3 Trials of Lemborexant, a Dual Orexin Receptor Antagonist for the Treatment of Insomnia;The Journal of Clinical Pharmacology;2023-01-17

3. Lemborexant levels in maternal serum, cord blood, and breast milk during pregnancy and lactation: A case report;Psychiatry and Clinical Neurosciences Reports;2023-01-06

4. Targeting Orexin Receptors for the Treatment of Insomnia: From Physiological Mechanisms to Current Clinical Evidence and Recommendations;Nature and Science of Sleep;2023-01

5. Efficacy and safety of lemborexant over 12 months in Asian adults with insomnia disorder;Sleep Medicine: X;2022-12