Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy
Author:
Affiliation:
1. Mass Spectrometry and BiophysicsMerck & Co., Inc. 2000 Galloping Hill Road Kenilworth NJ 07033 USA
2. Pharmaceutical SciencesMerck & Co., Inc. 770 Sumneytown Pike West Point PA 19486 USA
Publisher
Wiley
Subject
Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201800631
Reference19 articles.
1. Profiling Formulated Monoclonal Antibodies by 1H NMR Spectroscopy
2. On the Analytical Superiority of 1D NMR for Fingerprinting the Higher Order Structure of Protein Therapeutics Compared to Multidimensional NMR Methods
3. Characterizing monoclonal antibody formulations in arginine glutamate solutions using 1H NMR spectroscopy
4. 2D 1HN, 15N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies
5. Multivariate Analysis of Two-Dimensional 1H, 13C Methyl NMR Spectra of Monoclonal Antibody Therapeutics To Facilitate Assessment of Higher Order Structure
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