Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

Author:

Delaine Tamara1,Collins Patrick2,MacKinnon Alison3,Sharma G.4,Stegmayr John4,Rajput Vishal K.1,Mandal Santanu1,Cumpstey Ian1,Larumbe Amaia1,Salameh Bader A.15,Kahl-Knutsson Barbro4,van Hattum Hilde6,van Scherpenzeel Monique67,Pieters Roland J.6,Sethi Tariq8,Schambye Hans9,Oredsson Stina10,Leffler Hakon4,Blanchard Helen2,Nilsson Ulf J.1

Affiliation:

1. Centre for Analysis and Synthesis; Department of Chemistry; Lund University; P. O. Box 124 221 00 Lund Sweden

2. Institute for Glycomics; Griffith University; Gold Coast Campus Queensland 4222 Australia

3. MRC Centre for Inflammation Research; The Queen's Medical Research Institute; University of Edinburgh; 49 Little France Crescent Edinburgh EH16 4TJ UK

4. Department of Laboratory Medicine; Section MIG; Lund University; BMC-C1228b Klinikgatan 28 221 84 Lund Sweden

5. Chemistry Department; The Hashemite University; P. O. Box 150459 Zarka 13115 Jordan

6. Department of Medicinal Chemistry and Chemical Biology; Utrecht Institute for Pharmaceutical Sciences; Utrecht University; P. O. Box 80082 3508 TB Utrecht Netherlands

7. Translational Metabolic Laboratory; 51 Radboud University Medical Center; P. O. Box 9101 6500 HB Nijmegen Netherlands

8. Department of Respiratory Medicine and Allergy; Kings College; 41 Denmark Hill Campus Bessemer Road London SE5 9RJ UK

9. Galecto Biotech ApS; COBIS; Ole Maaloes vej 3 Copenhagen N 2200 Denmark

10. Department of Biology; Lund University; P. O. Box 118 221 00 Lund Sweden

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

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