The Phormidolide Biosynthetic Gene Cluster: Atrans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide-Reference-Cited by-同舟云学术

The Phormidolide Biosynthetic Gene Cluster: Atrans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide

Published:2015-12-23 Issue:2 Volume:17 Page:164-173
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Bertin Matthew J.¹,Vulpanovici Alexandra²,Monroe Emily A.³,Korobeynikov Anton⁴,Sherman David H.⁵,Gerwick Lena¹,Gerwick William H.⁶

Affiliation:

1. Center for Marine Biotechnology and Biomedicine; Scripps Institution of Oceanography; University of California San Diego; 9500 Gilman Drive MC 0212 La Jolla CA 92093 USA

2. Department of Biochemistry and Biophysics; Oregon State University; 2011 Agricultural and Life Sciences; 2750 SW Campus Way Corvallis OR 97331 USA

3. Department of Biology; William Paterson University; 300 Pompton Road Wayne NJ 07470 USA

4. The Center for Algorithmic Biotechnology; Department of Statistical Modeling; St. Petersburg State University; Universitetskiy 28 Stary Peterhof St. Petersburg 198504 Russia

5. Life Sciences Institute; Department of Medicinal Chemistry; Department of Chemistry; Department of Microbiology and Immunology; University of Michigan; 4008 Life Sciences Institute; 210 Washtenaw Avenue Ann Arbor MI 48109 USA

6. Center for Marine Biotechnology and Biomedicine; Scripps Institution of Oceanography; Skaggs School of Pharmacy and Pharmaceutical Sciences; University of California San Diego; 9500 Gilman Drive, MC 0212 La Jolla CA 92093 USA) address

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference61 articles.

1. The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria

2. Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine Cyanobacterium Phormidium sp.

3. PhD thesis 2013

4. The chemistry and biology of fatty acid, polyketide, and nonribosomal peptide biosynthesis

5. Constructing Polyketides: From Collie to Combinatorial Biosynthesis

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