Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1)-Reference-Cited by-同舟云学术

Negative Cooperativity in NAD(P)H Quinone Oxidoreductase 1 (NQO1)

Published:2019-09-20 Issue:22 Volume:20 Page:2841-2849
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Megarity Clare F.¹^ORCID,Abdel‐Aal Bettley Hoda²,Caraher M. Clare¹²,Scott Katherine A.²^ORCID,Whitehead Roger C.³,Jowitt Thomas A.⁴,Gutierrez Aldo⁵,Bryce Richard A.²^ORCID,Nolan Karen A.²,Stratford Ian J.²^ORCID,Timson David J.¹⁶^ORCID

Affiliation:

1. School of Biological SciencesQueen's University BelfastMedical Biology Centre 97 Lisburn Road Belfast BT9 7BL UK

2. Manchester Pharmacy SchoolThe University of Manchester Oxford Road Manchester M13 9PL UK

3. Department of ChemistryThe University of Manchester Oxford Road Manchester M13 9PL UK

4. The Faculty of Life ScienceManchester Cancer Research Centre and the University of Manchester Oxford Road Manchester M13 9PT UK

5. School of Science and TechnologyNottingham Trent University Clifton Campus Nottingham NG11 8NS UK

6. School of Pharmacy and Biomolecular Sciences, Huxley BuildingUniversity of Brighton Lewes Road Brighton BN2 4GJ UK

Funder

Medical Research Council

Association for International Cancer Research

Department of Education and Learning, Northern Ireland

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201900313

Reference85 articles.

2. The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction.

3. NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms

4. DT-diaphorase as a quinone reductase: A cellular control device against semiquinone and superoxide radical formation

5. [30] DT-diaphorase: Purification, properties, and function

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