Investigating the Binding Mode of an Inhibitor of the MBNL1⋅RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder-Reference-Cited by-同舟云学术

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Investigating the Binding Mode of an Inhibitor of the MBNL1⋅RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder

Published:2012-10-24 Issue:17 Volume:13 Page:2505-2509
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Wong Chun-Ho,Richardson Stacie L.,Ho Yen-Jun,Lucas Alex M. H.,Tuccinardi Tiziano,Baranger Anne M.,Zimmerman Steven C.

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference61 articles.

1. Recognition of the DNA minor groove by pyrrole-imidazole polyamides

2. Molecular recognition of DNA by small molecules

3. Recognition of Mismatched Base Pairs in DNA

4. A structural analysis of G-quadruplex/ligand interactions

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1. Multiple hydrogen bonding driven supramolecular architectures and their biomedical applications;Chemical Society Reviews;2024

2. Cognate RNA-Binding Modes by the Alternative-Splicing Regulator MBNL1 Inferred from Molecular Dynamics;International Journal of Molecular Sciences;2022-12-18

3. A Selective Alkylating Agent for CTG Repeats in Myotonic Dystrophy Type 1;ACS Chemical Biology;2022-04-28

4. Molecular Therapies for Myotonic Dystrophy Type 1: From Small Drugs to Gene Editing;International Journal of Molecular Sciences;2022-04-21

5. A Novel Minor Groove Binder as a Potential Therapeutic Agent for Myotonic Dystrophy Type 1;ChemMedChem;2021-06-10

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