Effect of cimetidine on prognosis after simple closure of perforated duodenal ulcer

Author:

Simpson C J1,Lamont G1,Macdonald I1,Smith I S1

Affiliation:

1. Department of Surgery, Victoria Infirmary, Glasgow, Scotland, UK

Abstract

Abstract A prospective controlled study in 60 patients undergoing simple closure of perforated duodenal ulcer demonstrated a significant (P > 0·05) benefit following postoperative cimetidine treatment, in terms of avoiding subsequent dyspeptic symptoms and complications of peptic ulcer disease. Thus cimetidine is recommended in the follow-up management of perforated duodenal ulcers.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference11 articles.

1. Surgical treatment of peptic ulcer in United States;Fineberg;Lancet,1981

2. Effect of cimetidine on surgery for duodenal ulcer;Wylie;Lancet,1981

3. Peforated peptic ulcer in the West of Scotland: a survey of 5343 cases during 1954–1963;MacKay;Br Med J,1966

4. Cimetidine and perforated peptic ulcers;MacKay;Gut,1981

5. Perforated peptic ulcer in the West of Scotland 1964–1967;MacKay;Br J Surg,1976

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