Short term routine antibiotic prophylaxis in surgery

Author:

Stokes E J1,Waterworth P M1,Franks V1,Watson B1,Clark C G1

Affiliation:

1. Department of Clinical Microbiology and Surgical Unit, University College Hospital, London

Abstract

Abstract The effect of two doses only of tobramycin (or gentamicin) plus lincomycin timed to cover the operative and immediate postoperative period was tested in a double blind trial. Evidence is presented that wound infection was reduced. No acquired bacterial resistance was encountered nor is this likely after such short term therapy. Routine use of this régime is recommended for all operations in which colonized viscera or infected body cavities have to be handled or opened.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference10 articles.

1. The prophylaxis of surgical infection; the effect of prophylactic antimicrobial drugs on the incidence of infection following potentially contaminated operations;Bernard;Surgery,1964

2. Comparative pharmacology of tobramycin and gentamicin in adult volunteers;Black,1974

3. Large doses of penicillin in the prevention of surgical wound infection;Campbell;Lancet,1965

4. The reduction of surgical wound infections by prophylactic parenteral cephaloridine;Evans;Br. J. Surg.,1973

5. Prevention of wound infection after appendicectomy;Gilmour;Lancet,1973

Cited by 68 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Use of Prophylactic Antibiotic Therapy in Oral Surgical Procedures: The Confusion and Controversy Continues — A Critical Review;Journal of the California Dental Association;2008-12-01

2. Preliminary Studies on the Impregnation of Silastic Elastomers with Antimicrobial Substances;Developmental Medicine & Child Neurology;2008-11-12

3. Antibiotic Prophylaxis in Shunt Surgery;Developmental Medicine & Child Neurology;2008-11-12

4. PERIOPERATIVE CARE;Surgery of the Anus, Rectum & Colon;2008

5. Fusiform Excision with Primary Closure;Complications of Dermatologic Surgery;1993

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3