A chloride-secreting papilloma in the gall-bladder a tumour of heterotopic intestinal epithelium containing paneth cells and enterochromaffine cells and associated with massive chloride loss: With a critical review of papilloma of the gall-bladder

Abstract

Abstract The case to be described is one of cholecystostomy for presumed mucocele in which, during a drainage period of thirty-four days, there was an excessive out-pouring of chloride and water; the source of this fluid was revealed only on subsequent cholecystectomy, when there was found in the gall-bladder a papilloma composed of intestinal epithelium. It is presented in detail on account of the difficulties in diagnosis, the peculiar biochemical behaviour, and the unique underlying pathology.