Experimental studies on the aetiology of acute scorpion pancreatitis

Author:

Bartholomew C12,McGeeney K F12,Murphy J J12,Fitzgerald O12,Sankaran H12

Affiliation:

1. Department of Medicine, University of the West Indies, General Hospital, Port of Spain

2. Departments of Medicine and Therapeutics and of Surgery, University College, Dublin

Abstract

Abstract This study examined the action of the venom of the scorpion Tityus trinitatis on the pancreas and gastrointestinal tract in anaesthetized dogs, on the isolated extracorporeal haemoperfised canine pancreas and on the isolated canine sphincter of Oddi. The venom induces exocrine secretion in both the isolated and intact pancreas and causes contraction of the isolated sphincter of Oddi. These results are discussed in relation to the pathogenesis of acute scorpion pancreatitis and possibly of some other form of acute pancreatitis.

Funder

Wellcome Trust, London

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference5 articles.

1. Acute scorpion pancreatitis in Trinidad;Bartholomew;Br. Med. J.,1970

2. A new method for determination of alpha amylase;Ceska;Experimentia,1969

3. The preparation and properties of two new chromogenic substrates of trypsin;Erlanger;Arch. Biochem.,1961

4. A working demonstration of isolated pancreatic perfusion;Fitzgerald;J. Physiol. (Lond.),1974

5. Some notes on scorpion poisoning in Trinidad;Waterman;Trans. R. Soc. Trop. Med. Hyg.,1938

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