Accuracy of aspiration cytology in the diagnosis of breast disease

Author:

Smallwood J1,Herbert A2,Guyert P3,Taylor I1

Affiliation:

1. University Surgical Unit, Southampton, UK

2. Department of Pathology, Southampton, UK

3. Department of Radiology, Southampton, UK

Abstract

Abstract The accuracy of fine needle aspiration cytology has been assessed in 480 consecutive breast lesions where definitive histology was later available. The results in terms of specificity and sensitivity have also been compared to mammography and clinical examination. With adequate smears aspiration cytology was 100 per cent specific with no false positive diagnosis. This compares with 15 false positive mammograms and 12 false positive diagnoses on clinical examination. Cytology was unsatisfactory in 36 per cent of benign lesions owing to poor cellularity of the sample but when considered with mammography and examination led to a reduction in biopsies for benign disease. A definitive cytological diagnosis of malignant tumours resulted in a reduction in frozen sections with a substantial saving of resources and improvement in patient counselling. No mastectomy was performed for benign disease.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference14 articles.

1. A clinicopathogenic study of atypical lesions of the breast;Ashikari;Cancer,1974

2. Diagnosis in carcinoma of the breast;Davies;Br J Surg,1977

3. An assessment of a scoring scheme for the pre-operative diagnosis of breast lumps;Smallwood;Ann Roy Coll Surg,1984

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