Twelve-hour liver preservation in the pig using hypothermia and hyperbaric oxygen

Abstract

Abstract In an attempt to prolong successful storage of the pig liver beyond the 6–8 hours previously described from this laboratory, the addition of cell-membranestabilizing drugs to the preserving solution and the use of a potassium-rich solution were investigated. Using simple hypothermia alone, 10- and 12-hour storage was unsuccessful. Using the previously described hypothermic technique, but with the addition of hyperbaric oxygen at 3 atmospheres absolute (A.T.A.), consistently successful 12-hour preservation was achieved.