Fabrication of a Composite Monolithic Column of Poly (IL@MOF) for Adsorption of Acacetin in Medicinal and Food Homologous Plants

Abstract

AbstractIn this study, a poly (IL@MOF) composite monolithic column was synthesized using a simple and easy method. By adjusting the ratio of monomers, porogenic agents and cross‐linking agents, a macroporous composite monolith composed of metal organic framework (MOF) and ionic liquids (IL) was constructed. It was used as a high‐performance solid phase extraction (SPE) sorbent for the extraction of acacetin from medicinal and food homologous plants. The proposed SPE‐HPLC method for determination of acacetin had the advantages of high precision (0.06∼1.00 %), wide linear range (0.01∼250 μg mL−1) and low detection limits (3.26 ng mL−1). The poly (IL@MOF) monolithic column had excellent repeatability as an adsorbent. After 300 adsorption/desorption cycles, the corresponding chromatographic signal had no obvious change. These results indicated that the poly (IL@MOF) composite monolithic column was an ideal adsorbents and that the proposed method had potential for the enrichment and purification of flavonoids from medicinal and food homologous plants.