Exploring the Diverse Biological Frontiers of Isoxazole: A Comprehensive Review of its Pharmacological Significance

Abstract

AbstractThis review delves into the multifaceted biological activity of isoxazole, a versatile heterocyclic compound that has garnered significant attention in the realm of medicinal chemistry. Isoxazole derivatives have exhibited a wide array of pharmacological properties, ranging from antimicrobial and anti‐inflammatory activities to anticancer and neuroprotective effects. This comprehensive examination aims to provide a detailed overview of the molecular mechanisms underlying the biological actions of isoxazole, exploring its potential as a promising scaffold for drug development. The review encompasses recent advancements, structure‐activity relationships, and key findings from both in vitro and in vivo studies, offering insights into the therapeutic potential of isoxazole in various disease contexts. By synthesizing the current state of knowledge, this article aims to serve as a valuable resource for researchers and practitioners interested in the medicinal significance of isoxazole and its derivatives.