Affiliation:
1. Department of Quality Assurance H. R. Patel Institute of Pharmaceutical Education and Research Shirpur 425 405 Dist. Dhule, Maharashtra India
2. Department of Pharmaceutical Chemistry H. R. Patel Institute of Pharmaceutical Education and Research Shirpur 425 405 Dist. Dhule, Maharashtra India
3. Department of Pharmaceutical Chemistry R. C. Patel Institute of Pharmaceutical Education and Research Shirpur 425 405 Dist. Dhule, Maharashtra India
Abstract
AbstractLuminescent carbon nanoparticles, such as carbon quantum dots (CQDs) and graphene quantum dots (GQDs), are increasingly utilized for sarcosine detection due to their exceptional water permeability, sustained luminescence, and biocompatibility. Sarcosine as a biomarker holds significance for therapeutic purposes and disease identification. Carbon‐based sensors offer eco‐friendliness, recyclability, and affordability, making them sustainable for sensing applications across various domains. Despite the widespread use of standard sensors for sarcosine measurement, they face limitations. This paper presents a focused review of recent developments in biosensors utilizing luminescent carbon quantum dots and graphene quantum dots for sarcosine detection. Key processes are characterized by their selectivity and sensitivity to different forms of sarcosine and interfering substances like metallic ions and amino acids. The significant reaction mechanisms and detection methods for sarcosine are outlined and compared. Additionally, the challenges in developing functionalized CQDs and GQDs for further investigation are explored. In summary, luminescent carbon nanoparticles offer a promising avenue for sarcosine detection, addressing limitations of standard sensors through their cost‐effectiveness, sensitivity, and rapid response, thus holding potential for diverse sensing applications.