High gestational folic acid supplementation prevents hypoxia‐ischemia‐induced caspase‐3 augmenting without changing synapsin and H3 methylation levels in the rat hippocampus

Author:

Deniz Bruna Ferrary12,Confortim Heloísa Deola12,Miguel Patrícia Maidana12ORCID,Bronauth Loise2,Fernandes Isabela R.3,Muotri Alysson R.3,Pereira Lenir Orlandi12ORCID

Affiliation:

1. Programa de Pós‐Graduação em Neurociências Universidade Federal do Rio Grande do Sul Porto Alegre Brazil

2. Departamento de Ciências Morfológicas Universidade Federal do Rio Grande do Sul Porto Alegre Brazil

3. Department of Pediatrics/Rady Children's Hospital San Diego Department of Cellular & Molecular Medicine Stem Cell Program University of California San Diego School of Medicine La Jolla CA USA

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul

Publisher

Wiley

Subject

Developmental Biology,Developmental Neuroscience

Reference45 articles.

1. Mechanisms of neurodegeneration after severe hypoxic-ischemic injury in the neonatal rat brain

2. Proteasome regulates transcription‐favoring histone methylation, acetylation and ubiquitination in long‐term synaptic plasticity;Bach S. V.;Neuroscience Letters,2015

3. High dietary folate in pregnant mice leads to pseudo‐MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short‐term memory impairment in offspring;Bahous R. H.;Human Molecular Genetics,2017

4. Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged ≥60 y in the United States

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