Cell‐free <scp>DNA</scp> analysis for recurrent respiratory papillomatosis: A case report-Reference-Cited by-同舟云学术

Cell‐free DNA analysis for recurrent respiratory papillomatosis: A case report

Published:2024-08 Issue:8 Volume:12 Page:
ISSN:2050-0904
Container-title:Clinical Case Reports
language:en
Short-container-title:Clinical Case Reports

Author:

Yamada Satoshi¹^ORCID,Kano Kotaro¹,Ishikawa Ryuji¹²,Imai Atsushi¹,Mochizuki Daiki¹,Morita Kotaro¹,Takeuchi Kazutaka¹,Takizawa Yoshinori¹,Kawasaki Hideya³,Misawa Kiyoshi¹^ORCID

Affiliation:

1. Department of Otolaryngology/Head and Neck Surgery Hamamatsu University School of Medicine Hamamatsu Japan

2. Department of Otolaryngology Yaizu City Hospital Yaizu Japan

3. Institute for NanoSuit Research, Preeminent Medical Photonics Education and Research Center Hamamatsu University School of Medicine Hamamatsu Japan

Abstract

Key Clinical MessageA 35‐year‐old male presented with recurrent respiratory papillomatosis. Human papillomavirus type 11 was detected from all sites of tumor tissue DNA by PCR. The pre‐surgery cell‐free DNA (cfDNA) viral load (3.33 × 103 copies/ng DNA) fell below the post‐surgical detection limits on achieving remission, suggesting cfDNA's potential as a biomarker.

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccr3.9268

Reference23 articles.

1. Long‐Term Follow‐up of Parenteral Bevacizumab In Patients with Recurrent Respiratory Papillomatosis

2. Laryngeal squamous cell papilloma is highly associated with human papillomavirus

3. Association between human papillomavirus particle production and the severity of recurrent respiratory papillomatosis

4. A Staging System for Assessing Severity of Disease and Response to Therapy in Recurrent Respiratory Papillomatosis

5. Longitudinal measurement of HPV copy number in cell-free DNA is associated with patient outcomes in HPV-positive oropharyngeal cancer