IDEA: Integrated Drug Expression Analysis—Integration of Gene Expression and Clinical Data for the Identification of Therapeutic Candidates-Reference-Cited by-同舟云学术

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IDEA: Integrated Drug Expression Analysis—Integration of Gene Expression and Clinical Data for the Identification of Therapeutic Candidates

Published:2015-06-18 Issue:7 Volume:4 Page:415-425
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Ung MH¹,Varn FS¹,Cheng C¹²³

Affiliation:

1. Department of Genetics, Geisel School of Medicine at DartmouthHanover New Hampshire USA

2. Institute for Quantitative Biomedical Sciences, Geisel School of Medicine at Dartmouth Lebanon New Hampshire USA

3. Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth Lebanon New Hampshire USA

Funder

NIH

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.51

Reference49 articles.

1. Computational Drug Repositioning: From Data to Therapeutics

2. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

3. Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data

4. Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease

5. Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

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2. In silicoframeworks for systematic pre-clinical screening of potential anti-leukemia therapeutics;Expert Opinion on Drug Discovery;2016-10-11

3. Application of pharmacologically induced transcriptomic profiles to interrogate PI3K-Akt-mTOR pathway activity associated with cancer patient prognosis;Oncotarget;2016-08-31

4. Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era;Briefings in Bioinformatics;2016-06-12

5. Integrated Drug Expression Analysis for leukemia: an integrated in silico and in vivo approach to drug discovery;The Pharmacogenomics Journal;2016-03-15

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