Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c

Author:

Liu Gang1,Cooley Marion A2,Nair Prema M1,Donovan Chantal1,Hsu Alan C1,Jarnicki Andrew G13,Haw Tatt Jhong1,Hansbro Nicole G1ORCID,Ge Qi4,Brown Alexandra C1,Tay Hock1,Foster Paul S1,Wark Peter A15,Horvat Jay C1,Bourke Jane E6,Grainge Chris L1,Argraves W Scott2,Oliver Brian G47,Knight Darryl A1,Burgess Janette K48,Hansbro Philip M1

Affiliation:

1. Priority Research Centre for Healthy Lungs; Hunter Medical Research Institute and The University of Newcastle; Newcastle New South Wales Australia

2. Department of Regenerative Medicine and Cell Biology; Medical University of South Carolina; Charleston SC USA

3. Department of Pharmacology and Therapeutics; University of Melbourne; Parkville Victoria Australia

4. Woolcock Institute of Medical Research, Discipline of Pharmacology; University of Sydney; Sydney New South Wales Australia

5. Department of Respiratory and Sleep Medicine; John Hunter Hospital; Newcastle New South Wales Australia

6. Biomedicine Discovery Institute, Department of Pharmacology; Monash University; Parkville Victoria Australia

7. School of Life Sciences; University of Technology Sydney; Sydney New South Wales Australia

8. University of Groningen, University Medical Centre Groningen, Department of Pathology and Medical Biology; Groningen Research Institute of Asthma and COPD; Groningen The Netherlands

Funder

National Health and Medical Research Council

Rosalind Franklin Fellowship

University of Groningen and the European Union

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference70 articles.

1. Th2 cytokine antagonists: potential treatments for severe asthma;Hansbro;Expert Opin Investig Drugs,2013

2. Cytokine/anti-cytokine therapy - novel treatments for asthma?;Hansbro;Br J Pharmacol,2011

3. Prevalence of bronchial hyperresponsiveness and asthma in a rural adult population;Woolcock;Thorax,1987

4. Asthma;Fanta;N Engl J Med,2009

5. Allergy and the lung;Passalacqua;Clin Exp Immunol,2008

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