Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP ‐activated protein kinase and induces breakdown of glycogen-Reference-Cited by-同舟云学术

Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP ‐activated protein kinase and induces breakdown of glycogen

Published:2021-08-11 Issue:12 Volume:69 Page:2828-2844
ISSN:0894-1491
Container-title:Glia
language:en
Short-container-title:Glia

Author:

Jakobsen Emil¹^ORCID,Andersen Jens V.¹^ORCID,Christensen Sofie K.¹^ORCID,Siamka Olga¹,Larsen Martin R.²^ORCID,Waagepetersen Helle S.¹^ORCID,Aldana Blanca I.¹^ORCID,Bak Lasse K.¹^ORCID

Affiliation:

1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences University of Copenhagen Copenhagen Denmark

2. Department of Biochemistry and Molecular Biology University of Southern Denmark Denmark

Funder

Hørslev-Fonden

Lundbeckfonden

Augustinus Fonden

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.24072

Reference76 articles.

1. Protein Phosphorylation and Prevention of Cytochrome Oxidase Inhibition by ATP: Coupled Mechanisms of Energy Metabolism Regulation

2. A Phosphodiesterase 2A Isoform Localized to Mitochondria Regulates Respiration

3. Cyclic AMP Produced inside Mitochondria Regulates Oxidative Phosphorylation

4. Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects

5. Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection

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