Lesinurad: Evaluation of Pharmacokinetic and Pharmacodynamic Interactions With Warfarin in Healthy Volunteers
Author:
Affiliation:
1. Ardea Biosciences, Inc; San Diego CA USA
2. AstraZeneca; Gaithersburg MD USA
Funder
AstraZeneca
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpdd.662/fullpdf
Reference18 articles.
1. Urate crystal deposition disease and gout-new therapies for an old problem-chapter 11;Girardet;Annu Rep Med Chem,2014
2. Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia;Fleischmann;Rheumatology (Oxf),2014
3. Pharmacokinetics, pharmacodynamics, and safety of lesinurad, a selective uric acid reabsorption inhibitor, in healthy adult males;Shen;Drug Des Devel Ther,2015
4. The effect of lesinurad in combination with allopurinol on serum uric acid levels in patients with gout;Baumgartner;J Clin Pharmacol,2018
5. Lesinurad monotherapy in gout patients intolerant to a xanthine oxidase inhibitor: a 6 month phase 3 clinical trial and extension study;Tausche;Rheumatology (Oxf).,2017
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