Importance of cytochromes in cyclization reactions: Quantum chemical study on a model reaction of proguanil to cycloguanil-Reference-Cited by-同舟云学术

Importance of cytochromes in cyclization reactions: Quantum chemical study on a model reaction of proguanil to cycloguanil

Published:2014-09-05 Issue:28 Volume:35 Page:2047-2055
ISSN:0192-8651
Container-title:Journal of Computational Chemistry
language:en
Short-container-title:J. Comput. Chem.

Author:

Arfeen Minhajul¹,Patel Dhilon S.¹,Abbat Sheenu²,Taxak Nikhil¹,Bharatam Prasad V.¹

Affiliation:

1. Department of Medicinal Chemistry; National Institute of Pharmaceutical Education and Research (NIPER); S. A. S. Nagar (Mohali) 160 062 Punjab India

2. Department of Pharmacoinformatics; National Institute of Pharmaceutical Education and Research (NIPER); S. A. S. Nagar (Mohali) 160 062 Punjab India

Publisher

Wiley

Subject

Computational Mathematics,General Chemistry

Reference95 articles.

1. Rearrangement reactions catalyzed by cytochrome P450s

2. Sequential Asymmetric Polyketide Heterocyclization Catalyzed by a Single Cytochrome P450 Monooxygenase (AurH)

3. In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes: Formation of Reactive Iminium and Quinone Type Metabolites

4. Oxidative N -Dealkylation: A Mannich Intermediate in the Formation of a New Metabolite of Lidocaine in Man

5. Rebeccamycin and Staurosporine Biosynthesis: Insight into the Mechanisms of the Flavin-Dependent Monooxygenases RebC and StaC

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