Novel synthetic route for 5-substituted 6-arylmethylluracils from 2,4,6-trichloropyrimidines
Author:
Publisher
Wiley
Subject
Organic Chemistry
Reference28 articles.
1. Synthesis and Antiviral Activity of 6-Benzyl Analogs of 1-[(2-Hydroxyethoxy)methyl]-5-(phenylthio)thymine (HEPT) as Potent and Selective Anti-HIV-1 Agents
2. Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro
3. Synthesis of 6-arylvinyl analogues of the HIV drugs SJ-3366 and Emivirine
4. Synthesis of Novel N-1 (Allyloxymethyl) Analogues of 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine) with Improved Activity Against HIV-1 and Its Mutants
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3. Facile and Efficient Synthesis of 3-Pyrimidinyl Oxindoles by Phase-Transfer-Catalyzed Regioselective Nucleophilic Aromatic Substitution;European Journal of Organic Chemistry;2018-08-06
4. Synthesis of Novel Fluoro Analogues of MKC442 as Microbicides;Journal of Medicinal Chemistry;2014-06-03
5. 6-(Arylmethyl)pyrimidin-4(3H)-ones: anthology and prospects of highly efficient anti-HIV agents;Russian Chemical Bulletin;2012-07
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