Cancer is not a risk factor for severe COVID‐19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities-Reference-Cited by-同舟云学术

Cancer is not a risk factor for severe COVID‐19 in children, except in patients with recent allogeneic hematopoietic stem cell transplantation or comorbidities

Published:2024-06-02 Issue:8 Volume:71 Page:
ISSN:1545-5009
Container-title:Pediatric Blood & Cancer
language:en
Short-container-title:Pediatric Blood & Cancer

Author:

Velasco Puyó Pablo¹^ORCID,Tagarro Alfredo²³⁴,Garcia‐Obregon Susana⁵⁶,Villate Olatz⁵,Moraleda Cinta²⁷,Huerta Aragonés Jorge⁸⁹¹⁰^ORCID,Bardón Cancho Eduardo J.⁸⁹¹⁰^ORCID,Faura Morros Anna¹¹,Galán‐Gómez Víctor¹²^ORCID,Escobar Fernández Laura¹³,Lendinez‐Molinos Francisco¹⁴^ORCID,Herrero Velasco Blanca¹⁵,Ureña Horno Laura¹⁶,Domínguez‐Pinilla Nerea¹⁷¹⁸,Pascual Gazquez Juan Francisco¹⁹,Nova Lozano Cristina²⁰,Osuna‐Marco Marta²¹,Marín‐Cruz Inés²²²³,Gomez Pastrana Irene⁷,Garcia de Andoin Barandiaran Nagore²⁴²⁵²⁶,Gallego Mingo Nerea²⁷,Portugal Rodríguez Raquel²⁸,Cañete Adela²⁹,Pareja León Marta³⁰,Castrillo Bustamante Sara³¹,Tallón García María³²,Gónzalez‐Prieto Almudena³³,Solé‐Rodríguez María³⁴,González Cruz Macarena³⁵,Soriano‐Arandes Antonio³⁶,Mota Miriam³⁷,Pérez‐Hoyos Santiago³⁷,Moreno Lucas¹^ORCID,Astigarraga Itziar⁵³⁸³⁹,

Affiliation:

1. Pediatric Oncology and Hematology Department Vall d'Hebron Barcelona Hospital Barcelona Spain

2. Fundación de Investigación Biomédica Hospital 12 de Octubre Instituto de Investigación 12 de Octubre (imas12) Madrid Spain

3. Department of Pediatrics Infanta Sofía University Hospital Fundación para la Investigación Biomédica e Innovación Hospital Universitario Infanta Sofía y Hospital del Henares (FIIB HUIS HHEN) Madrid Spain

4. Universidad Europea de Madrid Madrid Spain

5. BioBizkaia Health Research Institute Pediatric Oncology Group Barakaldo Spain

6. UPV/EHU, Physiology Department Universidad del País Vasco/Euskal Herriko Unibertsitatea Leioa Spain

7. Pediatric Infectious Disease Unit Hospital Universitario 12 de Octubre Madrid Spain

8. Paediatrics Department Paediatric and Adolescent Haematology and Oncology Section Hospital Materno‐Infantil del Complejo Hospitalario General Universitario Gregorio Marañón Madrid Spain

9. Faculty of Medicine Universidad Complutense de Madrid Madrid Spain

10. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM) Madrid Spain

11. Pediatric Oncology and Hematology Unit Hospital Sant Joan de Déu Barcelona Spain

12. Pediatric Oncology and Hematology Department Hospital Infantil Universitario La Paz Madrid Spain

13. Pediatric Oncology and Hematology Department Hospital Clínico Universitario de Valladolid Valladolid Spain

14. Pediatric Oncology and Hematology Department Hospital Infantil Infanta Leonor Almería Spain

15. Pediatric Oncology and Hematology Unit Hospital Infantil Universitario del Niño Jesús Madrid Spain

16. Hospital Doctor Balmis de Alicante Alicante Spain

17. Pediatric Oncology Unit Complejo Hospitalario de Toledo Toledo Spain

18. i+12 Research Institute Hospital 12 de Octubre Madrid Spain

19. Pediatric Oncology and Hematology Department Hospital Universitario Virgen de las Nieves Granada Spain

20. Hospital Clínico Universitario Valencia Valencia Spain

21. Pediatric Oncology and Hematology Unit HM Hospitals Madrid Spain

22. Paediatric Infectious Diseases Rheumatology and Immunology Department Hospital Universitario Virgen del Rocío Sevilla Spain

23. Congenital Alterations of Immunity Group Infectious Diseases and Immune System Area Instituto de Biomedicina de Sevilla Sevilla Spain

24. Pediatric Oncology and Hematology Unit Donostia University Hospital San Sebastián Spain

25. Biogipuzkoa Health Research Institute Pediatric Group, Paseo Dr. Begiristain San Sebastián Spain

26. UPV/EHU, Pediatric Department Paseo Dr. J. Beguiristain Universidad del País Vasco/Euskal Herriko Unibertsitatea San Sebastian Spain

27. Paediatrics Department Hospital Universitario Son Espases Mallorca Spain

28. Pediatric Oncology and Hematology Department Hospital Universitario de Burgos Burgos Spain

29. Pediatric Oncology and Hematology Department Hospital Universitario y Politécnico La Fe Valencia Spain

30. Paediatrics Department Hospital General de Albacete Albacete Spain

31. Paediatrics Department Complejo Asistencial de Segovia Segovia Spain

32. Hospital Álvaro Cunqueiro Vigo Spain

33. Pediatric Oncology and Hematology Department Hospital Universitario de Salamanca Salamanca Spain

34. Hospital Universitario Juan Ramón Jiménez Huelva Spain

35. Paediatrics Department Hospital Universitario de Canarias Tenerife Spain

36. Pediatric Infectious Diseases and Immunodeficiencies Unit Vall d'Hebron Institut de Recerca Universitat Autònoma de Barcelona Hospital Vall d'Hebron Barcelona Catalonia Spain

37. Unit of Statistics and Bioinformatics (UEB) Vall d'Hebron Research Institute (VHIR) Barcelona Spain

38. Department of Pediatrics Hospital Universitario Cruces Barakaldo Spain

39. UPV/EHU, Department of Pediatrics Universidad del País Vasco/Euskal Herriko Unibertsitatea Barakaldo Spain

Abstract

AbstractThe EPICO (Spanish general registry of COVID‐19 in children)‐SEHOP (Spanish Society of Pediatric Hematology and Oncology) platform gathers data from children with SARS‐CoV‐2 in Spain, allowing comparison between children with cancer or allogeneic hematopoietic stem cell transplantation (alloHSCT) and those without. The infection is milder in the cancer/alloHSCT group than in children without comorbidities (7.1% vs. 14.7%), except in children with recent alloHSCT (less than 300 days), of which 35.7% experienced severe COVID‐19. These data have been shared with the SEHOP members to support treatment and isolation policies akin to those for children without cancer, except for those with recent alloHSCT or additional comorbidities. This highlights the collaborative registries potential in managing pandemic emergencies.

Funder

Instituto de Salud Carlos III

Asociación Española de Pediatría

European Commission

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pbc.31120

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