New Irreversible α‐ l ‐Iduronidase Inhibitors and Activity‐Based Probes-Reference-Cited by-同舟云学术

New Irreversible α‐ l ‐Iduronidase Inhibitors and Activity‐Based Probes

Published:2018-11-26 Issue:71 Volume:24 Page:19081-19088
ISSN:0947-6539
Container-title:Chemistry – A European Journal
language:en
Short-container-title:Chemistry A European J

Author:

Artola Marta¹^ORCID,Kuo Chi‐Lin²^ORCID,McMahon Stephen A.³,Oehler Verena³,Hansen Thomas¹^ORCID,van der Lienden Martijn²,He Xu⁴,van den Elst Hans¹,Florea Bogdan I.¹,Kermode Allison R.⁴,van der Marel Gijsbert A.¹,Gloster Tracey M.³,Codée Jeroen D. C.¹^ORCID,Overkleeft Herman S.¹^ORCID,Aerts Johannes M. F. G.²^ORCID

Affiliation:

1. Department of Bio-organic Synthesis Leiden Institute of Chemistry Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands

2. Department of Medical Biochemistry Leiden Institute of Chemistry Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands

3. Biomedical Sciences Research Complex School of Biology University of St Andrews North Haugh St Andrews Fife KY16 9ST UK

4. Department of Biological Sciences Simon Fraser University 8888 University Drive Burnaby BC V5A 1S6 Canada

Funder

H2020 European Research Council

Genzyme

Publisher

Wiley

Subject

General Chemistry,Catalysis,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.201804662

Reference27 articles.

1. The carbohydrate-active enzymes database (CAZy) in 2013

2. Family 39 α-l-Iduronidases and β-d-Xylosidases React through Similar Glycosyl−Enzyme Intermediates: Identification of the Human Iduronidase Nucleophile

3. Mucopolysaccharide diseases: A complex interplay between neuroinflammation, microglial activation and adaptive immunity

4. The mucopolysaccharidoses: a success of molecular medicine

5. Human α-l-iduronidase uses its ownN-glycan as a substrate-binding and catalytic module

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