Human immunodeficiency virus Type‐1 single‐stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia-Reference-Cited by-同舟云学术

Human immunodeficiency virus Type‐1 single‐stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia

Published:2018-12-24 Issue:5 Volume:67 Page:802-824
ISSN:0894-1491
Container-title:Glia
language:en
Short-container-title:Glia

Author:

Rawat Pratima¹,Teodorof‐Diedrich Carmen¹,Spector Stephen A.¹²^ORCID

Affiliation:

1. Department of Pediatrics, Division of Infectious DiseasesUniversity of California San Diego La Jolla California

2. Rady Children's Hospital San Diego California

Funder

National Institute of Neurological Disorders and Stroke

National Institute of Allergy and Infectious Diseases

National Institute of Mental Health

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.23568

Reference78 articles.

1. Single-Stranded RNA Derived from HIV-1 Serves as a Potent Activator of NK Cells

2. Prevalence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy

3. The immunosuppressant drug FK506 is a potent trophic agent for human fetal neurons

4. The NLRP3 Inflammasome Is Upregulated in HIV-Infected Antiretroviral Therapy-Treated Individuals with Defective Immune Recovery

5. NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223

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