Islet amyloid polypeptide acts on glucose- stimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca2+ concentration, and insulin secretion
Author:
Publisher
Wiley
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/dmrr.1140/fullpdf
Reference35 articles.
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2. Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes;Clark;Lancet,1987
3. The pancreatic islet cells in insular amyloidosis in human diabetic and non-diabetic adults;Westermark;Acta Pathol Microbiol Scand A,1973
4. Longitudinal studies on the development of diabetes in individual Macaca nigra;Howard;Diabetologia,1986
5. Evidence for proteotoxicity in beta-cells in type 2 diabetes: toxic islet amyloid polypeptide oligomers form intracellularly in the secretory pathway;Gurlo;Am J Pathol,2010
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