Rapid MALDI-TOF molecular imaging: Instrument enhancements and their practical consequences

Author:

Vestal Marvin1ORCID,Li Lingjun23ORCID,Dobrinskikh Evgenia4,Shi Yatao2,Wang Bowen5,Shi Xudong6,Li Sicheng1,Vestal Christina1,Parker Kenneth1

Affiliation:

1. SimulTOF Systems; Virgin Instruments Corp; Marlborough Massachusetts 01752

2. School of Pharmacy; University of Wisconsin-Madison; Madison Wisconsin 53705

3. Department of Chemistry; University of Wisconsin-Madison; Madison Wisconsin 53706

4. Colorado University; Denver Colorado 80045

5. Davis Heart and Lung Research Institute; The Ohio State University; Columbus Ohio 43210

6. Department of Surgery, School of Medicine and Public Health; University of Wisconsin-Madison; Madison Wisconsin 53705

Publisher

Wiley

Subject

Spectroscopy

Reference9 articles.

1. Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS;Caprioli;Anal Chem,1997

2. High spatial resolution imaging mass spectrometry of human optic nerve lipids and proteins;Anderson;J am Soc Mass Spectrom,2015

3. Pathophysiology of Langerhans cells;Jaitley;J Oral Maxillofac Pathol,2012

4. Quantitative mass spectrometry imaging (QMS) of endogenous insulin in mouse pancreas using modified insulin. Application note #MSI-01;Hamm;Imabiotech,2013

5. Direct profiling and identification of peptide expression differences in the pancreas of control and ob/ob mice by imaging mass spectrometry;Minerva;Proteomics,2008

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