Impaired suppression of synovial fluid CD4+CD25− T cells from patients with juvenile idiopathic arthritis by CD4+CD25+ Treg cells

Author:

Haufe Susanne,Haug Markus,Schepp Carsten,Kuemmerle-Deschner Jasmin,Hansmann Sandra,Rieber Nikolaus,Tzaribachev Nikolay,Hospach Toni,Maier Jan,Dannecker Guenther E.,Holzer Ursula

Funder

DFG

Rosemarie-Germscheid-Stiftung

Juergen Manchot Stiftung

Wyeth/Pfizer Pharma

Publisher

Wiley

Subject

Pharmacology (medical),Immunology,Rheumatology,Immunology and Allergy

Reference34 articles.

1. Juvenile idiopathic arthritis;Ravelli;Lancet,2007

2. Juvenile chronic arthritis;Woo;Lancet,1998

3. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol,1995

4. CD4+CD25+ regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid;Van Amelsfort;Arthritis Rheum,2004

5. CD4+CD25high regulatory cells in human peripheral blood;Baecher-Allan;J Immunol,2001

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