Finding the Dose for Hydroxychloroquine Prophylaxis for COVID‐19: The Desperate Search for Effectiveness

Author:

Al‐Kofahi Mahmoud1,Jacobson Pamala1,Boulware David R.2,Matas Arthur3,Kandaswamy Raja3,Jaber Mutaz M.1,Rajasingham Radha2,Young Jo‐Anne H.2,Nicol Melanie R.1

Affiliation:

1. Department of Experimental and Clinical Pharmacology College of Pharmacy University of Minnesota Minneapolis Minnesota USA

2. Department of Medicine Medical School University of Minnesota Minneapolis Minnesota USA

3. Department of Surgery Medical School University of Minnesota Minneapolis Minnesota USA

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference14 articles.

1. Discovering drugs to treat coronavirus disease 2019 (COVID-19)

2. Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro

3. In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2);Yao X.;Clin. Infect. Dis.

4. Towards optimization of hydroxychloroquine dosing in intensive care unit COVID‐19 patients;Perinel S.;Clin. Infect. Dis.

5. Optimizing Hydroxychloroquine Dosing for Patients With COVID‐19: An Integrative Modeling Approach for Effective Drug Repurposing

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