Affiliation:
1. Department of Ophthalmology Jeonbuk National University Medical School Jeonju Republic of Korea
2. Research Institute of Clinical Medicine of Jeonbuk National University—Biomedical Research Institute of Jeonbuk National University Hospital Jeonju Republic of Korea
3. Department of Otorhinolaryngology‐Head and Neck Surgery Jeonbuk National University Medical School Jeonju Republic of Korea
4. Department of Medical Informatics Jeonbuk National University Medical School Jeonju Republic of Korea
Abstract
ObjectivesTo investigate the bidirectional association between sudden sensorineural hearing loss (SSNHL) and open‐angle glaucoma (OAG) over a 12‐year follow‐up period using nationwide, population‐based data.MethodsThe study was conducted using the National Health Information Database of the National Health Insurance Service (NHIS‐NHID), which covered 3.5 million individuals from 2008 to 2019. In Study 1, we evaluated the effect of OAG on SSNHL, and in Study 2, we evaluated the effect of SSNHL on OAG. Participants of the control group were enrolled through “greedy nearest‐neighbor” 1:1 propensity score matching.ResultsIn Study 1, 26,777 people were included in each group. The hazard ratio (HR) for SSNHL of the OAG group was 1.27 (95% confidence interval [CI], 1.15–1.39). In subgroup analysis, there was significant HR value regarding (old age: 1.17, hyperlipidemia: 1.19). In Study 2, 15,433 people were included in each group. The HR for OAG of the SSNHL group was 1.18 (95% CI, 1.07–1.30). In subgroup analysis, the HRs were significant for old age (2.31), hypertension (1.17), diabetes (1.39), and hyperlipidemia (1.26).ConclusionOver the 12‐year follow‐up, we found a bidirectional association between SSNHL and OAG, suggesting a shared pathogenesis.Level of evidenceN/A. Laryngoscope, 133:3169–3177, 2023
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1 articles.
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