Combined administration of levetiracetam and valproic acid attenuates age-related hyperactivity of CA3 place cells, reduces place field area, and increases spatial information content in aged rat hippocampus-Reference-Cited by-同舟云学术

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Combined administration of levetiracetam and valproic acid attenuates age-related hyperactivity of CA3 place cells, reduces place field area, and increases spatial information content in aged rat hippocampus

Published:2015-07-14 Issue:12 Volume:25 Page:1541-1555
ISSN:1050-9631
Container-title:Hippocampus
language:en
Short-container-title:Hippocampus

Author:

Robitsek Jonathan¹,Ratner Marcia H.¹,Stewart Tara¹,Eichenbaum Howard²,Farb David H.¹

Affiliation:

1. Laboratory of Molecular Neurobiology; Department of Pharmacology and Experimental Therapeutics; Boston University School of Medicine; Boston Massachusetts

2. Department of Psychology; Center for Memory and Brain; Boston University; Boston Massachusetts

Funder

NIA

NIGMS

Boston University Center for Neuroscience Seed Fund

Publisher

Wiley

Subject

Cognitive Neuroscience

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/hipo.22474/fullpdf

Reference61 articles.

1. Place cells in the hippocampus: Eleven maps for eleven rooms;Alme;Proc Natl Acad Sci USA,2014

2. Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment;Bakker;Neuron,2012

3. Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance;Bakker;Neuroimage Clin,2015

4. Loss of place specificity in hippocampal complex spike cells of senescent rat;Barnes;Neurobiol Aging,1983

5. Neuropsychological deficits associated with route learning in alzheimer disease, MCI, and normal aging;Benke;Alzheimer Dis Assoc Disord,2014

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