Chronic exposure to arsenic, estrogen, and their combination causes increased growth and transformation in human prostate epithelial cells potentially by hypermethylation-mediated silencing of MLH1

Author:

Treas Justin1,Tyagi Tulika1,Singh Kamaleshwar P.1

Affiliation:

1. Department of Environmental Toxicology, The Institute of Environmental and Human Health (TIEHH); Texas Tech University; Lubbock Texas

Publisher

Wiley

Subject

Urology,Oncology

Reference49 articles.

1. Epidemiology and risk factors of the prostate cancer;Stasiewicz;Pol Merkur Lekarski,2012

2. Prostate development and carcinogenesis;Wong;Int Rev Cytol,2003

3. Environmental causes of cancer: Endocrine disruptors as carcinogens;Soto;Nat Rev Endocrinol,2010

4. Role of estrogens in development of prostate cancer;Harkonen;J Steroid Biochem Mol Biol,2004

5. Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra;Timms;Proc Natl Acad Sci USA,2005

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