Affiliation:
1. Department of Respiratory and Critical Care Medicine Binzhou Medical College Affiliated Hospital (First Clinical Medical College) Binzhou China
2. Department of Pathology Binzhou Medical College Affiliated Hospital Binzhou China
3. Department of Imaging Binzhou Medical College Affiliated Hospital Binzhou China
Abstract
AbstractPleural mesothelioma (PM) with pericardial involvement is extremely rare. We now report a rare case of malignant PM with constrictive pericarditis as the first presentation. A 59‐year‐old male diagnosed with constrictive pericarditis underwent pericardiectomy and pericardial pathology revealed mesothelial hyperplasia. Eight months after surgery, the patient was admitted to the hospital with chest tightness and wheezing for 5 days. Computed tomography scan of the chest showed a left lung expansion insufficiency, limited bilateral pleural thickening, pericardial thickening with a small amount of pericardial effusion, and multiple enlarged lymph nodes in the mediastinum, bilateral supraclavicular fossa, bilateral cervical roots, and right axilla. The pleural malignancy should be possibly considered. Pathology after pleural puncture showed malignant PM. Pathology after left supraclavicular lymph node puncture biopsy showed metastatic malignant mesothelioma. The diagnosis of this patient was clear. Although malignant PM rarely involves the pericardial constriction, we cannot ignore the fact that malignant PM involves the pericardium. The patient has been diagnosed with constrictive pericarditis, accompanied by pleural thickening and pleural effusion. Without other pathogenic factors, pleural biopsy should be aggressively performed in patients with constrictive pericarditis to determine the cause.
Reference13 articles.
1. Synchronous pleural and peritoneal malignant mesothelioma: a case report and review of literature;Del GA;Int J Clin Exp Pathol,2014
2. Pericardial mesothelioma presenting as constrictive pericarditis;Shrestha B;Cureus,2022
3. Primary Spinal Malignant Mesothelioma: A Case Report and Literature Review
4. Malignant Pleural Mesothelioma presenting with Cardiac Tamponade- A Rare Case report and Review of the literature
5. Diffuse Malignant Mesothelioma