Separation and preparative purification of l ‐ and d ‐valine ester: Diastereomeric conjugates of atazanavir using a combination of 2‐propanol and acetonitrile in reversed‐phase high‐performance liquid chromatography

Author:

Shyamsundar Murugesan1,Chauthe Siddheshwar Kisan1,Subramani Lakshumanan2,Subbaiah Murugaiah A. M.2,Gupta Anuradha3ORCID,Bajpai Lakshmikant4,Bagadi Muralidhararao1ORCID,Mathur Arvind5

Affiliation:

1. Discovery Analytical Sciences Biocon Bristol Myers Squibb Research & Development Center (BBRC) Bangalore India

2. Department of Medicinal Chemistry Biocon Bristol Myers Squibb Research & Development Center (BBRC) Bangalore India

3. Department of Discovery Synthesis Biocon Bristol Myers Squibb Research & Development Center (BBRC) Bangalore India

4. Analytical Research & Development Biocon Bristol Myers Squibb Research & Development Center (BBRC) Bangalore India

5. Small Molecule Drug Discovery Bristol Myers Squibb Research and Development Princeton New Jersey USA

Publisher

Wiley

Reference33 articles.

1. Chiral drugs: An Overview;Nguyen LA;Int J Biomed Sci,2006

2. The market of chiral drugs: Chiral switches versus de novo enantiomerically pure compounds

3. Importance of chirality in drug therapy and pharmacy practice: implications for psychiatry;Davies NM;Adv Pharm,2003

4. Separation of enantiomers: needs, challenges, perspectives

5. Chirality and its implications for the pharmaceutical industry

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