Affiliation:
1. Department of Otolaryngology–Head and Neck Surgery, Princess Margaret Cancer Centre University Health Network Toronto Ontario Canada
2. Department of Surgical Oncology, Princess Margaret Cancer Centre University Health Network Toronto Ontario Canada
Abstract
AbstractObjectiveTreatment options for recurrent early glottic carcinoma's include conservative and radical surgical options. These options offer similar survival benefits with different impacts of patient's quality of life. We previously present our experience with vertical partial laryngectomy (VPL) and showed high locoregional control rates with high‐quality voice results and normal swallowing.Study DesignA long‐term retrospective review.SettingTertiary Care Center.MethodsWe analyzed all patients underwent VPL between the years 1995 to 2018. Long‐term oncologic and functional outcomes were collected.ResultsA total of 40 patients were included. The majority of whom were male (n = 38, 95%) with a mean age of 64.9 years (SD ± 9.5). With a median follow up time of 12 years (range 0‐24), 9 patients (22.5%) had disease recurrence; the majority of whom (8 patients), had local recurrence and all were salvaged with total laryngectomy. Eight patients (20%) developed second primaries in the head and neck region with a median time to diagnosis of 77 months (range 8‐227 months). Ten‐years overall survival, disease specific survival, and local disease‐free survival were 80%, 90%, and 80%, respectively. Five patients had postoperative laryngeal dysfunction with a total 10‐years laryngectomy free survival of 70%.ConclusionVPL has a sustainable oncologic outcome with a high long‐term laryngectomy free survival rate. This entity is an acceptable conservative salvage option for selected postradiated recurrent laryngeal squamous cell carcinoma patients.