Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance-Reference-Cited by-同舟云学术

Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance

Published:2015-11-25 Issue:7 Volume:138 Page:1645-1656
ISSN:0020-7136
Container-title:International Journal of Cancer
language:en
Short-container-title:Int. J. Cancer

Author:

Wojtuszkiewicz Anna¹²,Raz Shachar³,Stark Michal³,Assaraf Yehuda G.³,Jansen Gerrit⁴,Peters Godefridus J.⁵,Sonneveld Edwin⁶,Kaspers Gertjan J. L.¹,Cloos Jacqueline¹²

Affiliation:

1. Department of Pediatric Oncology/Hematology; VU University Medical Center; Amsterdam The Netherlands

2. Department Of Hematology; VU University Medical Center; Amsterdam The Netherlands

3. Department Of Biology; Technion-Israel Institute of Technology; Haifa Israel

4. Department Of Rheumatology; VU University Medical Center; Amsterdam The Netherlands

5. Department Of Medical Oncology; VU University Medical Center; Amsterdam The Netherlands

6. Dutch Childhood Oncology Group (DCOG); The Hague The Netherlands

Funder

KiKa (Children cancer-free) and Vonk (VUmc Onderzoek Naar Kinderkanker)

Publisher

Wiley

Subject

Cancer Research,Oncology

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2. Long-term outcome in children with relapsed ALL by risk-stratified salvage therapy: results of trial acute lymphoblastic leukemia-relapse study of the Berlin-Frankfurt-Munster Group 87;Einsiedel;J Clin Oncol,2005

3. Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia;Rots;Br J Haematol,2000

4. Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance;Gonen;Drug Resist Updat,2012

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