Affiliation:
1. Department of Emergency Medicine the Affiliated Hospital of Xuzhou Medical University Xuzhou 221002 Jiangsu China
2. Department of Emergency Medicine, The Second People's Hospital of Huai'an The Affiliated Huai'an Hospital of Xuzhou Medical University Huai'an 223002 Jiangsu China
3. Department of Neurology, Huai'an First People's Hospital The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University Huai'an 223300 Jiangsu China
4. Department of Emergency Medicine Suining People's Hospital Xuzhou 221000 Jiangsu China
Abstract
AbstractObjectiveTo compare the efficacy of intermittent hemodialysis (IHD) and continuous veno‐venous hemofiltration (CVVH) in patients with chronic renal failure complicated by massive intracerebral hemorrhage.MethodsSixty‐two patients were randomly and equally divided into IHD and CVVH groups. The clinical variables were compared, including National Institutes of Health Stroke Scale (NIHSS) score as the primary indicator, cerebral edema volume, hospital‐acquired pneumonia (HAP) incidence, acute heart failure (AHF) incidence, rehemorrhage incidence, hospital stay length, and modified Rankin Scale (mRS) score.ResultsThe CVVH group had lower NIHSS scores and edema volumes than the IHD group on postoperative days 7 and 14. Moreover, in the CVVH group, (i) the NIHSS scores on postoperative days 3 and 7 were higher than those on postoperative day 1; (ii) there was no significant difference in NIHSS scores between days 14 and 1; and (iii) no significant difference in cerebral edema volume was found between postoperative days 1 and 3, 7, and 14. In the IHD group, the NIHSS scores and cerebral edema volume on postoperative days 7 and 14 were significantly higher than those on postoperative day 1. The CVVH group had a lower incidence of HAP, AHF, and adverse events and shorter hospital stay length than the IHD group. The proportions of patients with mRS scores of 1 and 2 in the CVVH group were higher than those in the IHD group on day 30 after discharge.InterpretationCVVH is more effective than IHD in the treatment of patients with chronic renal failure complicated by massive intracerebral hemorrhage.
Funder
Jiangsu Provincial Commission of Health and Family Planning
Subject
Neurology (clinical),General Neuroscience