Glycopeptide Synthesis Based on a TFA-Labile Protection Strategy and One-Pot Four-Segment Ligation for the Synthesis of O-Glycosylated Histone H2A
Author:
Affiliation:
1. Institute for Protein Research; Osaka University; Yamadaoka 3-2, Suita Osaka 565-0871 Japan
Funder
Japan Society for the Promotion of Science
Publisher
Wiley
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://onlinelibrary.wiley.com/doi/am-pdf/10.1002%2Fejoc.201801885
Reference67 articles.
1. Chromatin modification and epigenetic reprogramming in mammalian development
2. Histone core modifications regulating nucleosome structure and dynamics
3. -N-acetylglucosamine (O-GlcNAc) is part of the histone code
4. GlcNAcylation of histone H2B facilitates its monoubiquitination
5. linking metabolism to epigenetics through O-GlcNAcylation
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