Affiliation:
1. Department of Materials and Life Sciences Faculty of Science and Technology Sophia University Chiyoda‐ku Tokyo Japan
2. Laboratory of Innovative Nanostructured Material (NANO: C) Faculty of Medicine and Pharmaceutical Sciences The University of Douala Douala Cameroon
3. Institute for Organic Chemistry and Structural Chemistry Heinrich‐Heine‐University Dusseldorf Dusseldorf Germany
4. Nanosciences African Network iThemba LABS‐National Research Foundation Cape Town South Africa
Abstract
ABSTRACTThis study examined the synthesis of silver nanoparticles (SNPs) with aqueous extracts of Cyclosorus dentatus and Nephrolepis biserrata fronds and the evaluation of their biological activities. Mixing of AgNO3 solution and the aqueous extracts resulted in color change, indicating the formation of SNPs. UV‐Vis spectroscopy analysis gave a surface plasmon resonance (SPR) peak at approximately 420 nm, confirming the presence of the synthesized SNPs. Infrared analysis showed C‐O, N‐O, and C‐C vibrations or stretching and aliphatic vibrations of hydrocarbon chains of the synthesized SNPs. x‐Ray diffraction (XRD) analysis indicated the SNPs were face‐centered, cubic, and crystalline in nature, with crystallite sizes. The scanning electron microscopy (SEM) shows the aggregation of the spherical shape nanoparticles. The SNPs significantly reduced phosphomolybdenum and captured H2O2 with respective IC50 values of 61.55 and 29.03 µg/mL for C. dentatus SNP (SNP‐Cd), and 92.61 and 9.07 µg/mL for N. biserrata SNP (SNP‐Nb), respectively. In terms of albumin‐denaturing activity, the SNPs gave an IC50 value of 21.20 µg/mL for SNP‐Cd and 7.18 µg/mL for SNP‐Nb. Thus, this work confirmed that SNP‐Cd and SNP‐Nb are potential therapeutic agents for treating oxidative stress, inflammatory problems, and related diseases.