Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer-Reference-Cited by-同舟云学术

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Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer

Published:2016-12-13 Issue:2 Volume:47 Page:385-393
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

van Hooren Luuk¹,Sandin Linda C.¹,Moskalev Igor²,Ellmark Peter³⁴,Dimberg Anna¹,Black Peter³,Tötterman Thomas H.¹,Mangsbo Sara M.¹

Affiliation:

1. Department of Immunology, Genetics and Pathology; Uppsala University; Uppsala Sweden

2. Vancouver Prostate Centre; University of British Columbia; Vancouver Canada

3. Alligator Bioscience AB; Lund Sweden

4. Department of Immunotechnology; Lund University; Lund Sweden

Funder

Svenska Sällskapet för Medicinsk Forskning

Vetenskapsrådet

Cancerfonden

Seventh Framework Programme

Göran Gustafssons Stiftelse för Naturvetenskaplig och Medicinsk Forskning

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference31 articles.

1. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy;Schwartz;Cell,1992

2. CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells;Quezada;J. Clin. Invest.,2006

3. Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function;Fecci;Clin. Cancer Res.,2007

4. Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma;Simpson;J. Exp. Med.,2013

5. Depleting tumor-specific Tregs at a single site eradicates disseminated tumors;Marabelle;J. Clin. Invest.,2013

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