Affiliation:
1. Department of Biology, Institute of Molecular Health Sciences Swiss Federal Institute of Technology Zurich (ETH Zurich) Zurich Switzerland
Abstract
The metastatic process is an extraordinarily complex step‐by‐step procedure, characterized by many analogies with migratory patterns of humans or animals across our planet. The ongoing interrogation of circulating tumor cells (CTCs), caught in the act of spreading from one location to another, is revealing distinct behaviors including biological, physical, and mechanical features that impact on their likelihood to form metastasis. In this viewpoint, I will discuss some of these findings and provide a perspective on the metastatic journey, open questions and opportunities to exploit some of the most recent discoveries for the development of antimetastasis medicines.
Funder
Eidgenössische Technische Hochschule Zürich
H2020 European Research Council
Krebsliga Schweiz
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Subject
Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology
Cited by
2 articles.
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