NEK2 induces autophagy‐mediated bortezomib resistance by stabilizing Beclin‐1 in multiple myeloma

Author:

Xia Jiliang12,He Yanjuan1,Meng Bin2,Chen Shilian2,Zhang Jingyu2,Wu Xuan2,Zhu Yinghong2,Shen Yi34,Feng Xiangling5,Guan Yongjun2,Kuang Chunmei2,Guo Jiaojiao2,Lei Qian2,Wu Yangbowen5,An Gang6,Li Guancheng2,Qiu Lugui6,Zhan Fenghuang4,Zhou Wen12ORCID

Affiliation:

1. Department of Hematology Xiangya Hospital Central South University Changsha China

2. Key Laboratory for Carcinogenesis and Invasion Chinese Ministry of Education Key Laboratory of Carcinogenesis Chinese Ministry of Health Cancer Research Institute School of Basic Medical Sciences Central South University Changsha China

3. Department of Orthopaedic Surgery Second Xiangya Hospital Central South University Changsha China

4. Department of Medicine Division of Hematology, Oncology and Blood and Marrow Transplantation Holden Comprehensive Cancer Center University of Iowa IA USA

5. Xiangya School of Public Health Central South University Changsha China

6. State Key Laboratory of Experimental Hematology Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Science & Peking Union Medical College Tianjin China

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

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