Nonsense‐mediated decay factor SMG7 sensitizes cells to TNFα‐induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1-Reference-Cited by-同舟云学术

Nonsense‐mediated decay factor SMG7 sensitizes cells to TNFα‐induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1

Published:2020-07-13 Issue:10 Volume:14 Page:2420-2435
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Mol Oncol

Author:

Yang Limeng¹,Kraft Vanessa A. N.¹^ORCID,Pfeiffer Susanne¹,Merl‐Pham Juliane²,Bao Xuanwen³,An Yu⁴,Hauck Stefanie M.²,Schick Joel A.¹^ORCID

Affiliation:

1. Genetics and Cellular Engineering Group Institute of Molecular Toxicology and Pharmacology Helmholtz Zentrum Munich GmbH German Research Center for Environmental Health Neuherberg Germany

2. Research Unit Protein Science Helmholtz Zentrum Munich GmbH German Research Center for Environmental Health Neuherberg Germany

3. Institute of Radiation Biology Helmholtz Zentrum Munich GmbH German Research Center for Environmental Health Neuherberg Germany

4. Department of Chinese Medicine National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China

Funder

China Scholarship Council

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.12754

Reference57 articles.

1. NMD: RNA biology meets human genetic medicine

2. Cancer syndromes and therapy by stop-codon readthrough

3. Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact