Ovarian cancer early detection by circulating CA125 in the context of anti-CA125 autoantibody levels: Results from the EPIC cohort

Author:

Fortner Renée T.1ORCID,Schock Helena1,Le Cornet Charlotte1,Hüsing Anika1,Vitonis Allison F.2,Johnson Theron S.1,Fichorova Raina N.34,Fashemi Titilayo4,Yamamoto Hidemi S.4,Tjønneland Anne5,Hansen Louise5,Overvad Kim6,Boutron-Ruault Marie-Christine789,Kvaskoff Marina789,Severi Gianluca78910,Boeing Heiner11,Trichopoulou Antonia1213,Papatesta Eleni-Maria12,La Vecchia Carlo1214ORCID,Palli Domenico15ORCID,Sieri Sabina16,Tumino Rosario17,Sacerdote Carlotta18ORCID,Mattiello Amalia19,Onland-Moret N. Charlotte20,Peeters Petra H.2021,Bueno-de-Mesquita H. Bas2223,Weiderpass Elisabete24252627,Quirós J. Ramón28,Duell Eric J.29ORCID,Sánchez Maria-Jose3031,Navarro Carmen3132,Ardanaz Eva313334,Larrañaga Nerea3135,Nodin Björn36,Jirström Karin36,Idahl Annika3738,Lundin Eva39,Khaw Kay-Tee40,Travis Ruth C.41,Gunter Marc42,Johansson Mattias42,Dossus Laure42,Merritt Melissa A.43,Riboli Elio43,Terry Kathryn L.23,Cramer Daniel W.23,Kaaks Rudolf1ORCID

Affiliation:

1. Division of Cancer Epidemiology; German Cancer Research Center (DKFZ); Heidelberg Germany

2. Ob/Gyn Epidemiology Center; Brigham and Women's Hospital; Boston MA

3. Obstetrics, Gynecology and Reproductive Biology; Harvard Medical School; Boston MA

4. Laboratory of Genital Tract Biology; Brigham and Women's Hospital; Boston MA

5. Unit of Diet, Genes and Environment; Danish Cancer Society Research Center; Copenhagen Denmark

6. Department of Public Health, Section for Epidemiology; Aarhus University; Aarhus Denmark

7. INSERM, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health team; Villejuif F-94805 France

8. Université Paris Sud, UMRS 1018; Villejuif F-94805 France

9. Gustave Roussy; Villejuif F-94805 France

10. Human Genetics Foundation (HuGeF); Torino Italy

11. Department of Epidemiology; German Institute of Human Nutrition Potsdam-Rehbruecke; Nuthetal Germany

12. Hellenic Health Foundation; Athens Greece

13. Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine; WHO Collaborating Center for Nutrition and Health, National and Kapodistrian University of Athens; Athens Greece

14. Department of Clinical Sciences and Community Health; Università degli Studi di Milano; Milan Italy

15. Cancer Risk Factors and Life-Style Epidemiology Unit; Cancer Research and Prevention Institute-ISPO; Florence Italy

16. Epidemiology and Prevention Unit; Fondazione IRCCS Istituto Nazionale dei Tumori; Milan Italy

17. Cancer Registry and Histopathology Unit; “Civic-M.P-Arezzo” Hospital; ASP Ragusa Italy

18. Unit of Cancer Epidemiology; Città della Salute e della Scienza University-Hospital and Center for Cancer Prevention (CPO); Turin Italy

19. Dipartimeno di Medicina Clinica e Chirurgia; Federico II University; Naples Italy

20. Department of Epidemiology; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht; Utrecht The Netherlands

21. MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health; Imperial College; London United Kingdom

22. Department for Determinants of Chronic Diseases (DCD); National Institute for Public Health and the Environment (RIVM); Bilthoven The Netherlands

23. Department of Epidemiology and Biostatistics, The School of Public Health; Imperial College London; London United Kingdom

24. Department of Community Medicine, Faculty of Health Sciences; University of Tromsø, The Arctic University of Norway; Tromsø Norway

25. Department of Research, Cancer Registry of Norway; Institute of Population-Based Cancer Research; Oslo Norway

26. Department of Medical Epidemiology and Biostatistics; Karolinska Institutet; Stockholm Sweden

27. Genetic Epidemiology Group; Folkhälsan Research Center; Helsinki Finland

28. Public Health Directorate; Asturias Spain

29. Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO); Barcelona Spain

30. Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada; Granada Spain

31. CIBER de Epidemiología y Salud Pública (CIBERESP); Spain

32. Department of Epidemiology; Murcia Regional Health Council, IMIB-Arrixaca; Murcia Spain

33. Navarra Public Health Institute; Pamplona Spain

34. IdiSNA, Navarra Institute for Health Research; Pamplona Spain

35. Public Health Division of Gipuzkoa; Regional Government of the Basque Country; Donostia Spain

36. Division of Oncology and Pathology, Department of Clinical Sciences Lund; Lund University; Lund Sweden

37. Department of Clinical Sciences, Obstetrics and Gynecology; Umeå University; Umeå Sweden

38. Department of Public Health and Clinical Medicine; Nutritional Research, Umeå University; Umeå Sweden

39. Department of Medical Biosciences, Pathology; Umeå University; Umeå Sweden

40. Cancer Epidemiology Unit; University of Cambridge; Cambridge United Kingdom

41. Cancer Epidemiology Unit; Nuffield Department of Population Health University of Oxford; Oxford United Kingdom

42. International Agency for Research on Cancer; Lyon France

43. Department of Epidemiology and Biostatistics, School of Public Health; Imperial College London; United Kingdom

Funder

National Cancer Institute

Publisher

Wiley

Subject

Cancer Research,Oncology

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