High Density Body Surface Potential Mapping with Conducting Polymer‐Eutectogel Electrode Arrays for ECG imaging

Author:

Serrano Ruben Ruiz‐Mateos1,Velasco‐Bosom Santiago1,Dominguez‐Alfaro Antonio12,Picchio Matias L.2,Mantione Daniele23,Mecerreyes David23,Malliaras George G.1ORCID

Affiliation:

1. Electrical Engineering Division University of Cambridge Cambridge CB3 0FA UK

2. POLYMAT University of the Basque Country UPV/EHU Avda. Tolosa 72 Donostia‐San Sebastian Gipuzkoa 20018 Spain

3. IKERBASQUE Basque Foundation for Science Bilbao 48009 Spain

Abstract

AbstractElectrocardiography imaging (ECGi) is a non‐invasive inverse reconstruction procedure which employs body surface potential maps (BSPM) obtained from surface electrode array measurements to improve the spatial resolution and interpretability of conventional electrocardiography (ECG) for the diagnosis of cardiac dysfunction. ECGi currently lacks precision, which has prevented its adoption in clinical setups. The introduction of high‐density electrode arrays could increase ECGi reconstruction accuracy but is not attempted before due to manufacturing and processing limitations. Advances in multiple fields have now enabled the implementation of such arrays which poses questions on optimal array design parameters for ECGi. In this work, a novel conducting polymer electrode manufacturing process on flexible substrates is proposed to achieve high‐density, mm‐sized, conformable, long‐term, and easily attachable electrode arrays for BSPM with parameters optimally selected for ECGi applications. Temporal, spectral, and correlation analysis are performed on a prototype array demonstrating the validity of the chosen parameters and the feasibility of high‐density BSPM, paving the way for ECGi devices fit for clinical application.

Funder

Engineering and Physical Sciences Research Council

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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