STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity-Reference-Cited by-同舟云学术

STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity

Published:2022-11-29 Issue:3 Volume:10 Page:2203718
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Advanced Science

Author:

Zhu Zhichuan¹²,Zhou Xin¹³,Du Hongwei¹³,Cloer Erica W.¹,Zhang Jiaming⁴,Mei Liu²,Wang Ying¹²,Tan Xianming¹⁵,Hepperla Austin J.¹⁶⁷,Simon Jeremy M.¹⁶⁷⁸,Cook Jeanette Gowen¹²,Major Michael B.⁹,Dotti Gianpietro¹³,Liu Pengda¹²^ORCID

Affiliation:

1. Lineberger Comprehensive Cancer Center The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

2. Department of Biochemistry and Biophysics The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

3. Department of Microbiology and Immunology The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

4. Department of Oral Medicine Infection and Immunity Harvard School of Dental Medicine Boston MA 02115 USA

5. Department of Biostatistics The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

6. Carolina Institute for Developmental Disabilities The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

7. UNC Neuroscience Center The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

8. Department of Genetics The University of North Carolina at Chapel Hill Chapel Hill NC 27599 USA

9. Department of Cell Biology and Physiology Department of Otolaryngology Washington University in St. Louis St. Louis MO 63130 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202203718

Reference81 articles.

1. Pathogen Recognition and Innate Immunity

2. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

3. DNA-induced liquid phase condensation of cGAS activates innate immune signaling

4. The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING

5. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

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