Survival‐Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah –/– Rag2 –/– IL2rg –/– Rats

Author:

Zhang Ludi1,Ge Jian‐Yun23,Zheng Yun‐Wen2345ORCID,Sun Zhen6,Wang Chenhua1,Peng Zhaoliang7,Wu Baihua1,Fang Mei4,Furuya Kinji2,Ma Xiaolong1,Shao Yanjiao8,Ohkohchi Nobuhiro2,Oda Tatsuya2,Fan Jianglin39,Pan Guoyu7,Li Dali8,Hui Lijian16101112

Affiliation:

1. State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences University of Chinese Academy of Science Shanghai 200031 China

2. Department of Gastrointestinal and Hepato‐Biliary‐Pancreatic Surgery, Faculty of Medicine University of Tsukuba Tsukuba Ibaraki 305‐8575 Japan

3. Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine School of Biotechnology and Heath Sciences Wuyi University Jiangmen Guangdong 529020 China

4. Institute of Regenerative Medicine Affiliated Hospital of Jiangsu University Jiangsu University Zhenjiang Jiangsu 212001 China

5. Yokohama City University School of Medicine Yokohama Kanagawa 234‐0006 Japan

6. School of Life Science and Technology ShanghaiTech University Shanghai 201210 China

7. Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China

8. Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences East China Normal University Shanghai 200241 China

9. Department of Molecular Pathology, Faculty of Medicine Interdisciplinary Graduate School of Medicine University of Yamanashi Shimokato Yamanashi 409‐3898 Japan

10. School of Life Science, Hangzhou Institute for Advanced Study University of Chinese Academy of Sciences Hangzhou 310024 China

11. Institute for Stem Cell and Regeneration Chinese Academy of Sciences Beijing 100101 China

12. Bio‐Research Innovation Center Shanghai Institute of Biochemistry and Cell Biology Suzhou Jiangsu 215121 China

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

Japan Society for the Promotion of Science

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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