A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells

Author:

Giglio Fabiana1ORCID,Scieuzo Carmen12ORCID,Ouazri Sofia1ORCID,Pucciarelli Valentina1ORCID,Ianniciello Dolores1,Letcher Sophia3ORCID,Salvia Rosanna12ORCID,Laginestra Ambrogio4,Kaplan David L.3ORCID,Falabella Patrizia12ORCID

Affiliation:

1. Department of Sciences University of Basilicata Via dell’Ateneo Lucano, 10 85100 Potenza Italy

2. Spinoff Xflies S.R.L University of Basilicata Viale dell’Ateneo Lucano 10 85100 Potenza Italy

3. Department of Biomedical Engineering School of Engineering Tufts University Colby Street, 4 Medford MA 02155 USA

4. Department of Relations with the Territory TotalEnergies EP Italia S.P.A Via della Tecnica, 4 85100 Potenza Italy

Abstract

The increasing global population and demand for meat have led to the need to find sustainable and viable alternatives to traditional production methods. One potential solution is cultivated meat (CM), which involves producing meat in vitro from animal stem cells to generate products with nutritional and sensory properties similar to conventional livestock‐derived meat. This article examines current approaches to CM production and investigates how using insect cells could enhance the process. Cell sources are a critical issue in CM production, alongside advances in culture media, bioreactors for scalability, and scaffold development. Insect cells, compared to commonly used mammalian cells, may offer advantages in overcoming technological challenges that hinder cell culture development and expansion. The objective of this review is to emphasize how insects, as a cell source for CM production, could offer a more sustainable option. A crucial aspect for achieving this goal is a comprehensive understanding of the physiology of muscle and fat cells. In this work, the characteristics of insect and mammalian cells are compared, focusing particularly on muscle and fat cell development, regulatory pathways, hormonal regulation, and tissue composition. Insect cells are a promising source for CM, offering a sustainable and environmentally friendly alternative.

Funder

Università degli Studi della Basilicata

Publisher

Wiley

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