Affiliation:
1. Department of Food Science and Engineering, Institute of Food Safety and Nutrition Jinan University Guangzhou P. R. China
2. The Sixth Affiliated Hospital Jinan University Dongguan P. R. China
3. School of Chemical Engineering and Light Industry Guangdong University of Technology Guangzhou P. R. China
4. Department of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine Jinan University Guangzhou P. R. China
Abstract
AbstractBlack soybean peels (BSPs) are rich in anthocyanins (ANCs), a naturally active substance added to manufactured foods. However, the instability of the ANC structure limits its application in the food industry. In the present study, an efficient and simple microencapsulation method to improve the stability of ANC was successfully established. BSP ANCs were encapsulated in a microencapsulated complex with fructo‐oligosaccharide (FOS) and whey protein (WP) associated with a high encapsulation rate (65.41%) and drug‐loading capacity (6.13%). The particle size and polydispersity index of anthocyanin‐loaded microencapsulation (ALM) were 4.648 ± 0.350 µm and 0.405 ± 0.107, respectively. The ANC stability test showed that ALM performed enhanced thermostability, pH stability, storage stability, and light stability. Meanwhile, in vitro release experiments indicated that ALM dramatically delayed the contact time of ANC with the environment and reduced the degradation. Moreover, animal experiments demonstrated that ALM better improved blood glucose homeostasis and lipid homeostasis in high‐fat‐ and high‐fructose‐treated mice and reduced liver lipid accumulation and damage. Additionally, the better in vivo bioactivity could be attributed to the extended bioavailability that was proved by a pharmacokinetics test. These results suggested that the microencapsulation employed WP‐FOS complexes as the wall materials are of great potential to improve the stability and health‐promoting properties of ANC, providing a promising solution as dietary supplementation.
Funder
Fundamental Research Funds for the Central Universities
National Natural Science Foundation of China
Cited by
2 articles.
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